Latest Publications

Loss of the batten disease protein CLN3 leadsto mis-trafficking of M6PR and defectiveautophagic-lysosomal reformation
Jul 03, 2023Nature Communications
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Increased expression or activation of TRPML1 reduces hepatic storage of toxic Z alpha-1 antitrypsin
Jul 01, 2023Molecular Therapy
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Synaptic mechanisms underlying onset and progression of memory deficits caused by hippocampal and midbrain synucleinopathy
Jun 16, 2023NPJ Parkinson's DIsease
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Cellular population dynamics shape the route to human pluripotency
May 17, 2023Nature Communications
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RagD auto-activating mutations impair MiT/TFE activity in kidney tubulopathy and cardiomyopathy syndrome
May 15, 2023Nature Communications
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Esrrb guides naive pluripotent cells through the formative transcriptional programme
Apr 27, 2023Nature Cell Biology
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EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation
Mar 08, 2023Plos Biology
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Events & Seminars
Senior lab manager position in Cacchiarelli's Lab
Jun 19, 2023Technician Position in Pastore’s Lab
Jun 09, 2023Postdoctoral position in Pastore's Lab
Jun 09, 2023PostDoctoral position available in Gambardella’s Lab
May 02, 2023PostDoctoral position available in Settembre's Lab
Feb 27, 2023Dissemination
The Scientific Office is the principal agent responsible for interacting with the public and coordinating all affairs related to dissemination and outreach.
Dissemination and visibility within the community allow TIGEM to share its initiatives in an open manner. Our activities reach the public in a variety of ways, allowing the community to see how we operate within our ethics code.
Carrying out research that has the possibility to change lives comes with a responsibility that we respect and treat with the upmost care. Not only do we adhere to a code of research ethics in our scientific activities, but we welcome the public to get to know our institute.
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