THE TELETHON INSTITUTE OF GENETICS AND MEDICINE
Quality research to understand the mechanisms behind rare genetic diseases
Welcome to TIGEM
The Telethon Institute of Genetics and Medicine (TIGEM) is a multidisciplinary research Institute devoted to studying the mechanisms underlying rare genetic diseases and to developing innovative therapies.
With the support of Fondazione Telethon, the European Community and many other funding agencies, TIGEM's research groups are engaged in numerous clinical trials and collaborative projects. In addition, TIGEM's alliances with various universities offer the Institute additional resources and provide opportunities for excellent students.

Our Vision
Our work aims to understand the causes of genetic disorders by unravelling the mechanisms that underpin them. We also aim to discover new ways to diagnose, prevent and treat these diseases, offering alternative and improved outcomes for patients.

Advancements in Gene Therapy Applications: From HSCs to Liver, Retinal and Mitochondrial Diseases
Nov 28, 2023Some researchers of us will have their speeches into the webinar organized by Miltenyi Biotec
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Progress in the study of a rare genetic syndrome with renal and cardiac alterations
Oct 05, 2023After the identification of the gene responsible for the syndrome, the mechanism underlying its onset was also described, opening the way to the study of new possible therapeutic strategies.
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Third worldwide convention of “Panettone artigianale”
Oct 04, 2023A very special moment to celebrate the excellence of Accademia dei Maestri del Lievito Madre e del Panettone Italiano and the Telethon Institute of Genetics and Medicine
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SSM Calls for the Undergraduate and PhD Programs
Jul 20, 2023The Scuola Superiore Meridionale (SSM) announces a public competition for admission to the Undergraduate and PhD programs for the academic year 2023/24!
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SEMM Calls for PhD Programs
Jul 18, 2023The European School of Molecular Medicine (SEMM) offers 70 PhD positions in the Systems Medicine program!
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A large international investment in hereditary retinal diseases
Jun 06, 2023The path of AAVantgarde Bio, the Tigem spin-off dedicated to the development of gene therapies for hereditary diseases of the retina, continues at full speed! The company, founded in 2021 thanks to the Sofinnova-Telethon fund, has in fact announced that it has obtained a 61 million euro from three major international investment companies: Atlas Venture, Forbion and Longwood. AAVantgarde Bio will work to bring an innovative gene therapy approach born in the Telethon laboratories to the clinic.
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EUROPEAN RESEARCH COUNCIL (ERC): ASSIGNED TO ANDREA BALLABIO AND ALBERTO AURICCHIO TWO ADVANCED GRANTS FOR A TOTAL OF 5 MILLION EUROS
Mar 30, 2023Andrea Ballabio and Alberto Auricchio received the prestigious ERC Advanced Grants, also as evidence of excellence of the Telethon Institute of Genetics and Medicine, capable of attracting the best Italian and international scientists.
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PhD Programs
TIGEM recognizes that the future of scientific research lies in the hands of young scientists committed to learning more and making key contributions to their fields.
To this end, TIGEM offers three PhD programmes for talented students who wish to pursue a career in medical science, thus supporting the next generation of scientists devoted to the study of rare genetic disorders and the provision of improved treatments and outcomes for patients.


