Paolo Grumati

Paolo Grumati

Cell Biology and Disease Mechanisms

Molecular Mechanisms of Autophagy




I have always been fascinated by the dynamics of cellular organelles: how they change shape, move inside the cell, and are constantly replaced. Gaps in understanding of the endoplasmic reticulum has led us to explore whether autophagy regulates ER turnover and if autophagy failure can cause severe human diseases.

Additional Funding
  • Modulating ER-phagy thwart muscle diseases (2022-2023). Muscular Dystrophy Association
  • Leading GLUT1 towards the plasma membrane (2022-2023) Telethon Foundation
  • MFAG - Dissecting selective autophagy role in oesophageal and colorectal neoplasia development (2021-2026)