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Career Opportunities

24/06/2020 Post Doctoral Position in Prof. Ballabio's Lab

Seeking candidatesfor a Postdoctoral training position in the Ballabiolab at the Telethon Institute of Genetics and Medicine.

Candidates must have a doctoral degree, at least 3 years of experience in the lab and excellent verbal and written communication skills.  Qualified candidates must have at least one first author paper published or accepted in a high profile peer- reviewed journal. Salary will be commensurate with experience.

The Ballabio lab is a multidisciplinary group involved in the following research topics: lysosomal function and dysfunction, lysosomal storage diseases, lysosomal signaling in cancer, regulation of mTORC1, regulation of  lysosomal biogenesis. Research approaches include molecular genetics, cell biology, biochemistry,  omics and in vivo studies in mouse models

TIGEM offers a strong international community experienced in cell biology, bioinformatics and in vivo studies.  In addition, research is supported by core facilities such as Advanced Microscopy, Next Generation Sequencing, Proteomics, High Content Screening, among others. 

TIGEM islocated in Pozzuoli, a beautiful town on the seavery close to Naples, in the “Olivetti” campus. Our structure is complete with a cafeteria, recreational space and gym.

For more information about Tigem please visit:

For more information about the lab of Andrea Ballabio, please visit:

Please send your CV and name of two referees at


24/06/2020 Bioinformatician Position Available in Tigem Bioinformatics Core

The TIGEM Bioinformatics Core ( is at the heart of bioinformatics research at TIGEM. The TIGEM BC currently consists of three researchers with Engineering, Biology and Mathematics background. TIGEM BC works side by side with TIGEM researchers to develop and apply state-of-the-art bioinformatics and biostatistical tools to advance research in genetic diseases as well as cancer and neurodegenerative disorders. As part of the TIGEM BC, we are looking for an enthusiastic bioinformatician with a specific expertise in NGS data analysis as an essential requirement. Salary is competitive and will be commensurate with the experience. Please apply by the 31st of July 2020 writing to Valeria Rotoli including your CV.

14/05/2020 | Translational Unit (TTU) Open Position available

TIGEM Translational Unit (TTU) is mainly dedicated to in vivo pre-clinical studies supporting the development of novel treatments for genetic and metabolic disorders.  

A research technician position is now available under the supervision of Dr Nunzia Pastore

Specific duties of the research technician will be to manage mouse colonies (breeding and genotyping) and perform in vitro and in vivo experiments. The individual for this job has to be highly organized, methodical and reliable. The salary will be negotiated based on applicant experience.

Required qualifications:

-      BSc or MSc degree in the area of biology;

-      Experience managing mouse breeding colony;

-      Experience with cell culture;

-      Knowledge of the principal molecular biology techniques;

Interested candidates are requested to send a CV to Dr. Nunzia Pastore at

13/05/2020 Position available in a BrightFocus Foundation Project

Position available on the BrightFocus Foundation project entitled “miR-181a/b modulation as potential therapeutic approach for AMD treatment”. 

Starting date: September 2020


We are looking for highly motivated candidates with expertise in mice biology and handling. Previous experience in retinal biology is highly desirable but not mandatory. Applications from candidates with pre- and post-doctoral experience, as well as more technical expertise are welcome. The salary will be negotiated based on applicant experience. We can provide a fellowship for a 2-year plan, yearly subjected to evaluation.


The candidate will work on an exciting project focused on the development of a new, RNA-based, gene-independent therapy for the treatment of Aged Macular Degeneration (AMD).

AMD is a common cause of blindness worldwide and the loss of vision is due to progressive loss of specific cell type of the eye important in the visual process. Genetic and environmental factors are involved in the onset and progression of this disease for which limited therapeutic strategies are available to date. This project aims to devise a therapeutic strategy that can be applied to a vast number of patients independently of the causative factor.


The Telethon Institute of Genetics and Medicine (TIGEM) located in Pozzuoli (Naples) is devoted to the study of mechanisms underlying rare genetic diseases and to the development of innovative therapies. The Institute is equipped with state-of-the-art instrumentation and facilities for biological research. 

Interested candidates are requested to send a CV and emails of 2 referees to:



Sabrina Carrella, PhD

Research Associate, Telethon Institute of Genetics and Medicine (TIGEM) 


University of Campania “Luigi Vanvitelli”





Alessia Indrieri, PhD

Telethon Institute of Genetics and Medicine 


Institute for Genetic and Biomedical Research (IRGB), CNR

Milan, Italy



19/02/2020 Post-doctoral position in Sorrentino's Group

Postdoctoral Position in inherited neurodegenerative disorders at TIGEM -Telethon institute of Genetics and Medicine of Pozzuoli 



A Postdoctoral position in the research group of Dr. Nicolina Cristina Sorrentino at TIGEM is available -Telethon Institute of Genetics and Medicine of Pozzuoli. The candidate will work on an exciting project focused on the development of new gene and drug therapy protocols for the treatment of systemic and neurodegenerative pathology in a mouse model of a very severe Lysosomal Storage Disorder, Mucopolysaccharidoses type IIIA (MPS-IIIA). 


We are seeking highly motivated Postdocs with demonstrated potential for creativity, with the ability to conduct their independent, self-directed, cutting-edge research in collaborative environment. In addition to leading his/her own project, the applicant will have the opportunity to contribute to other projects in the lab and to develop and participate in external collaborations. 



Basic Qualifications


Biological/Biotechnology degree 

PhD in a related-relevant field


Good Track record in Molecular Biology and Gene Therapy fields and experience in handling and working with mouse models.


Good English oral and written skills are a must.


Good communication skills and the capability to work in team.


Additional Qualifications

The candidate should have hands-on experiencein molecular, biochemical and immunohistochemical techniques.


The candidate should have good knowledge and experience in immunofluorescence microscopy and also cells cultures. 



Applications & Contact

Short motivation letter and CV should be addressed to Dr. Nicolina Cristina Sorrentino (mail:


Reference literature

Sorrentino NC et al., Mol Ther Methods Clin Dev. 2019doi: 10.1016/j.omtm.2019.10.009.

Sorrentino NC et al., Pediatr Endocrinol Rev. 2016. Suppl 1:630-8. Review.

Sorrentino NC et al., EMBO Mol Med. 2013.  doi: 10.1002/emmm.201202083.

09/12/19 Postgraduate Fellow Position Available in Fraldi's lab

We are seeking a highly motivated postgraduate fellow (Master Degree in Biological Science, Medical Biotechnology, Medicine, or Pharmacy) to work in the laboratory led by Dr. Alessandro Fraldi, at the Telethon Institute of Genetics and Medicine in Naples, Italy. The lab is part of the Molecular Therapy program and is interested in mechanisms underlying neurodegeneration in lysosomal storage diseases (a class of inherited metabolic diseases) and in developing new therapeutic approaches to treat the CNS in these disorders.

We can provide a fellowship for 2 year (yearly subjected to evaluation).

Please send via mail CV and 2 reference letters to: 

Alessandro Fraldi, PhD (

Antonio Monaco (

25/11/2019 Post-doctoral position in Brunetti-Pierri’s laboratory

We are seeking a postdoctoral fellow with a Master Degree  in Biological Science, Medical Biotechnology, Medicine, or Pharmacy and a PhD level in the field of biomedical science to be part of team at TIGEM. The candidate will be responsible of a research project aiming at generating preclinical data supporting the development of novel treatments for inborn errors of metabolism.  Written and oral skills of communications English (minimum level B1) are mandatory. We can provide a fellowship for n. 2 year plan, yearly subjected to evaluation. Please send via mail CV and n.3 reference letters to: Nicola Brunetti-Pierri, MD, e-mail: