Chiara Di Malta

Chiara Di Malta

Cell Biology and Disease Mechanisms

Lysosomal signaling and metabolism




We intend to dissect how lysosomal dysfunction contributes to kidney cystogenesis and cancer in order to open up new therapeutic avenues for the treatment of these conditions. At TIGEM, we can pursue these goals supported by high-quality resources and facilities, in an international and extremely stimulating environment.

Additional Funding
  • Defining the molecular mechanisms underlying MiT/TFE-associated kidney cancer. (2023-2027), My First AIRC Award
  • Targeting TFEB transcription factor as a novel therapeutic approach for the treatment of Birt-Hogg-Dube'-associated kidney cancer (2021-2023), Wordwide Cancer Research