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OnlineSeminar - Diego Luis Medina, PhD - "Repurposing approaches to tackle LSDs"

Assistant Investigator, Tigem and Associate Professor of Biology, University of Naples “Federico II”, Naples, Italy
When Apr 20, 2021
from 12:00 PM to 01:15 PM
Where TigemOnlineSeminar
Contact Name
Contact Phone 08119230659
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Abstract
Lysosomal storage diseases are a group of metabolic disorders caused by deficiencies of several components of lysosomal function. Novel technologies, in most cases based on high-throughput approaches have significantly contributed to the characterization of lysosomal biology or lysosomal dysfunction and have the potential to facilitate diagnostic processes, enable the identification of new therapeutic targets, and are instrumental for the screening of compounds to correct these diseases. We have successfully combined cell-based High Content Imaging (HCI) approaches with the repurposing of FDA approved compounds to discover novel therapeutic options for two LSDs. 


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