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Noboru Mizushima, M.D., Ph.D. - "Physiological roles and molecular mechanisms of autophagy."

(Professor, Department of Biochemistry and Molecular Biology, Graduate School and Faculty of Medicine, The University of Tokyo, Japan)
When Jul 20, 2016
from 12:00 PM to 01:00 PM
Where Tigem Auditorium "Vesuvius"
Contact Name
Contact Phone 08119230659
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CURRICULUM VITAE

Publications (selected)

  1. Kaizuka, T., *Mizushima, N. Atg13 is essential for autophagy and cardiac development in mice. Mol. Cell. Biol. 36: 585-595 (2015).
  2. Suzuki, H., Kaizuka, T.,*Mizushima, N., *Noda, N. N. Structure of the Atg101–Atg13 complex reveals essential roles of Atg101 in mammalian autophagy initiation. Nat. Struct. Mol. Biol. 22: 572–580 (2015).
  3. Saitsu, H., Nishimura, T., Muramatsu, K., Kodera, H., Kumada, S., Sugai, K., Kasai-Yoshida, E., Sawaura, N., Nishida, H., Hoshino, A., Ryujin, F., Yoshioka, S., Nishiyama, K., Kondo, Y., Tsurusaki, Y., Nakashima, M., Miyake, N., Arakawa, H., Kato, M., *Mizushima, N., *Matsumoto, N. De novo mutations in the autophagy gene encoding WDR45 (WIPI4) cause static encephalopathy of childhood with neurodegeneration in adulthood. Nat. Genet. 45: 445-449 (2013).
  4. Itakura, E., Kishi-Itakura, C., Mizushima, N. The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell 151: 1256-1269 (2012).
  5. Takamura, A., Komatsu, M., Hara, T., Sakamoto, A., Kishi, C., Waguri, S., Eishi, Y., Hino, O., Tanaka, K., Mizushima, N. Autophagy-deficient mice develop multiple liver tumors. Genes Dev. 25: 795-800 (2011)

 

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