Irene Bozzoni, M.Sc. - "From coding to no-coding RNAs and back"
May 09, 2017
from 12:00 PM to 01:30 PM
|Where||tigem Auditorium "Vesuvius"|
|Contact Name||Davide Cacchiarelli|
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High-throughput transcriptome analysis has revealed that the mammalian genome is pervasively transcribed into many different complex families of RNAs; even among the polyadenylated species, half resulted to be non-protein-coding RNAs. Moreover, it has been recently shown that quite a considerable number of transcripts have an unusual circular form. These novel RNAs are emerging as crucial players in the control of differentiation and development and their deregulation has been linked to several inherited and acquired disorders. I will show how these new classes of transcripts impinge on muscle function in normal and disease conditions and how they control gene expression.