You are here: Home / Research / Upcoming Seminars / Ganna Panasyuk, PhD - "Growth and Metabolic Control by PI3K Signalling"

Ganna Panasyuk, PhD - "Growth and Metabolic Control by PI3K Signalling"

Necker Enfants Malades Institute (INEM), Inserm, Faculté de Médecine Paris Descartes, Paris, France
When Nov 22, 2018
from 12:00 PM to 01:30 PM
Where Tigem, Vesuvius Auditorium
Contact Name
Contact Phone 081-19230659
Add event to calendar vCal
iCal

Short CV

Abstract
The research interests of my team belong to a fast evolving field on the crossroads of physiology, signal transduction and metabolism. Our overarching aim is to elucidate molecular mechanisms of metabolic control and its implication in human disease. Metabolic misbalance accompanies and contributes to a number of pathological conditions including so prevailing today obesity, type 2 diabetes and cancer. We focus on evolutionary conserved signalling cascade of Insulin Receptor and Phosphoinositide 3-Kinase (PI3K) in physiology and its implication in pathologies such as fatty liver disease, lysosomal storage disease and liver cancer. In this seminar, I will present our recent findings on the metabolic outcomes of interrogating hepatic pro-anabolic class 1 PI3K signalling and pro-catabolic class 3 PI3K signalling. I will also share our unpublished observations on the transcriptional control of liver metabolism by class 3 PI3K in adaptation to fasting.

Filed under: