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mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy

Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano AC, Monfregola J, De Gennaro E, Nusco E, Azario I, Lanzara C, Serafini M, Levine B, Ballabio A, Settembre C.

mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy.

J Clin Invest. 2017 Sep 5. pii: 94130. doi: 10.1172/JCI94130. [Epub ahead of print]