Brunella Franco | MD
Principal Investigator, TIGEM
Associate Professor of Medical Genetics, Department of Pediatrics, Università degli Studi di Napoli Federico II, Naples, Italy
Secretariat phone: +39 081 6132207
Fax: +39 081 5609877
Research Interests:
Research Group:
PostDoc: Daniela Iaconis, Alessia Indrieri, Manuela Morleo
Ph.D. Student: Marianna Buonaiuto, Cinzia Caprio, Alessia Romano, Maria Pia Turturo, Immacolata Piscopo
Undergraduate Student: Filomena Massa
Technician: Francesco Salierno, Roberta Tammaro
Selected Publications:
Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B (2011). Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol349: 179-191.
Zullo A, Iaconis D, Barra A, Cantone A, Messaddeq N, Capasso G, Dollé P, Igarashi P, Franco B (2010). Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathway. Hum Mol Genet19: 2792-2803.
Prattichizzo C, Macca M, Novelli V, Giorgio G, Barra A, Franco B (2008). Mutational spectrum of the Oral-facial-digital type I syndrome: a study on a large collection of patients. Hum Mutat29: 1237-1246.
Giorgio G, Alfieri M, Prattichizzo C, Zullo A, Cairo S, Franco B (2007). Functional characterization of the OFD1 protein reveals a nuclear localization and physical interaction with subunits of a chromatin remodeling complex. Mol Biol Cell18: 4397-4404.
Ferrante MI, Zullo A, Barra A, Bimonte S, Messaddeq N, Studer M, Dolle P, Franco B (2006). Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification. Nat Genet38: 112-117.