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Career Opportunities

07/06/2019 - 4-year post-doctoral position in Cacchiarelli’s laboratory

We are looking for a highly motivated post-doctoral fellow to work in the Armenise/Harvard laboratory of Integrative Genomics led by Dr. Davide Cacchiarelli, at the Telethon Institute of Genetics and Medicine in Naples, Italy. The lab is part of the Genomic medicine program and is interested in multifaceted approaches that combine several genomic strategies to study the regulatory logic driving human cell fate differentiation, conversion and reprogramming.
The candidate will work on an exciting project funded by a European Research Council grant and the position will be available from September 1st, 2019. The successful applicant must be a computational biologist or bioinformatician with excellent skills in transcriptomics and/or epigenomics. The candidate will work on the analysis of NGS data (bulk and single-cell RNAseq, ATACseq, WES and WGS, ChIPseq) and will be required to use previously developed algorithms and to develop new ones. 
The ideal candidate should enjoy problem solving, be persistent, resourceful and self-motivated. An ability to work independently is vital. Good English skills (oral and written) are a must. The Post-doc fellow will become part of an interdisciplinary research team consisting of PhD students, postdocs and master students. The position will be granted for four years with possibility of extension. The salary will be negotiated based on applicant past achievements.
The project relies on the in-house NGS (Next Generation Sequencing) and Bioinformatic cores, both supported by dedicated teams of Post-docs and technicians to carry out routine and special analyses with a long-standing expertise and cutting-edge technology. NGS facility takes advantage of NovaSeq 6000 and MiSeq sequencing systems supplied by Illumina. The Bioinformatic core supports TIGEM’s research community in addressing a wide variety of biological questions, from genomics and transcriptomics to statistical data analysis, using state-of-the-art computational approaches, plus an adequate hardware equipment for parallel computing and terabytes of storage space to manage and analyze such data.

  • a relevant PhD in genomics, computational biology, bioinformatics or equivalent qualification/experience in a related field of study;
  • strong knowledge of RNAseq and/or epigenomics data analysis and enthusiastic interest in solving biological problems;
  • capacity to analyze and interpret single-cell genomics data is a plus;
  • good English skills (oral and written).
Please send your CV, a letter of intent, a summary of previous research interests and achievements, and contacts of at least two reference letters to Prof. Davide Cacchiarelli:

Reference literature
Cacchiarelli et al, Cell.2015 Jul;162(2):412-424. doi: 10.1016/j.cell.2015.06.016
Trapnell et al, Nat Biotechnol.2014 Apr;32(4):381-386. doi: 10.1038/nbt.2859. 
Cacchiarelli et al, Cell Syst.2018 Sep;7(3):258-268.e3. doi: 10.1016/j.cels.2018.07.006

10/04/2019 | Open position available in Franco's lab

L’istituto Telethon di Genetica e Medicina (TIGEM) a Pozzuoli è focalizzato sullo studio dei meccanismi alla base di malattie genetiche rare e sullo sviluppo di terapie innovative. L’istituto è equipaggiato con strumentazione all’avanguardia e si avvale di un competitivo programma di dottorato internazionale in collaborazione con la Scuola Europea di medicina Molecolare (SEMM).

È disponibile presso il laboratorio della Prof.ssa Franco al TIGEM una posizione di  tirocinio per un giovane neolaureato/a altamente motivato/a e con esperienza in biologia cellulare e molecolare. Il candidato sarà coinvolto in un progetto per lo studio delle basi molecolari di malattie associate a disfunzione ciliare.

I candidati interessati devono inviare una lettera di motivazione, il CV e l’indirizzo email di 2 persone che possano fornire referenze a:

Dr. Brunella Franco
Prof Medical Genetics, Federico II University of Naples
Principal Investigator, (TIGEM)
Web site


Manuela Morleo, Associate Researcher

Publicazione rappresentative del laboratorio includono 

25/11/2019 Post-doctoral position in Brunetti-Pierri’s laboratory

We are seeking a postdoctoral fellow with a Master Degree  in Biological Science, Medical Biotechnology, Medicine, or Pharmacy and a PhD level in the field of biomedical science to be part of team at TIGEM. The candidate will be responsible of a research project aiming at generating preclinical data supporting the development of novel treatments for inborn errors of metabolism.  Written and oral skills of communications English (minimum level B1) are mandatory. We can provide a fellowship for n. 2 year plan, yearly subjected to evaluation. Please send via mail CV and n.3 reference letters to: Nicola Brunetti-Pierri, MD, e-mail:

17/09/19 Master Student Positions Available in Banfi's lab

One/two Master student positions are available in Prof Sandro Banfi’s laboratory at Telethon Institute of Genetics and Medicine (TIGEM) located in Pozzuoli (Naples). The candidate will be involved in a project aimed at the validation of the therapeutic efficacy of specific microRNA modulation in models of retinal degeneration.  

Interested candidates are requested to send a CV to:


Prof. Sandro Banfi
Professor of Medical Genetics, University of Campania “Luigi Vanvitelli"
Associate Investigator, Telethon Institute of Genetics and Medicine (TIGEM) email:


and to


Dr. Sabrina Carrella

Research Associate, Telethon Institute of Genetics and Medicine (TIGEM) and University of Campania “Luigi Vanvitelli”


07/11/19 Master Student Positions Available in Piccolo's lab

Master student positions are available in dr. Pasquale Piccolo’s laboratory at Telethon Institute of Genetics and Medicine (TIGEM) located in Pozzuoli (Naples). Students will be involved in a project aimed at the development of a liver-directed gene therapy approach for Wilson disease.  

Interested candidates are requested to send their CV, including modules and grades to:

12/11/19 Master Student Positions Available in Auricchio's lab

A Master student position is available in Prof. Alberto Auricchio’s laboratory at Telethon Institute of Genetics and Medicine (TIGEM).
The laboratory is located in the Department of Translational Medicine in via Sergio Pansini, 5 Naples.
The selected student will be involved in a project aimed at isolation and characterization of novel porcine AAV serotypes. 

The period of internship will be approximately 2 years

Interested candidates are requested to send a CV to Dr. Emanuela Pone at:


09/12/19 Postgraduate Fellow Position Available in Fraldi's lab

We are seeking a highly motivated postgraduate fellow (Master Degree in Biological Science, Medical Biotechnology, Medicine, or Pharmacy) to work in the laboratory led by Dr. Alessandro Fraldi, at the Telethon Institute of Genetics and Medicine in Naples, Italy. The lab is part of the Molecular Therapy program and is interested in mechanisms underlying neurodegeneration in lysosomal storage diseases (a class of inherited metabolic diseases) and in developing new therapeutic approaches to treat the CNS in these disorders.

We can provide a fellowship for 2 year (yearly subjected to evaluation).

Please send via mail CV and 2 reference letters to: 

Alessandro Fraldi, PhD (

Antonio Monaco (

19/02/2020 Post-doctoral position in Sorrentino's Group

Postdoctoral Position in inherited neurodegenerative disorders at TIGEM -Telethon institute of Genetics and Medicine of Pozzuoli 



A Postdoctoral position in the research group of Dr. Nicolina Cristina Sorrentino at TIGEM is available -Telethon Institute of Genetics and Medicine of Pozzuoli. The candidate will work on an exciting project focused on the development of new gene and drug therapy protocols for the treatment of systemic and neurodegenerative pathology in a mouse model of a very severe Lysosomal Storage Disorder, Mucopolysaccharidoses type IIIA (MPS-IIIA). 


We are seeking highly motivated Postdocs with demonstrated potential for creativity, with the ability to conduct their independent, self-directed, cutting-edge research in collaborative environment. In addition to leading his/her own project, the applicant will have the opportunity to contribute to other projects in the lab and to develop and participate in external collaborations. 



Basic Qualifications


Biological/Biotechnology degree 

PhD in a related-relevant field


Good Track record in Molecular Biology and Gene Therapy fields and experience in handling and working with mouse models.


Good English oral and written skills are a must.


Good communication skills and the capability to work in team.


Additional Qualifications

The candidate should have hands-on experiencein molecular, biochemical and immunohistochemical techniques.


The candidate should have good knowledge and experience in immunofluorescence microscopy and also cells cultures. 



Applications & Contact

Short motivation letter and CV should be addressed to Dr. Nicolina Cristina Sorrentino (mail:


Reference literature

Sorrentino NC et al., Mol Ther Methods Clin Dev. 2019doi: 10.1016/j.omtm.2019.10.009.

Sorrentino NC et al., Pediatr Endocrinol Rev. 2016. Suppl 1:630-8. Review.

Sorrentino NC et al., EMBO Mol Med. 2013.  doi: 10.1002/emmm.201202083.